Creatinine (Fixed Rate)

INTENDED USE

NS Biotec creatinine reagent is intended for the in vitro quantitative determination of creatinine in serum, plasma and urine on both automated and manual systems.

ASSAY PRINCIPLE

In 1886 Jaffé described a method for the measurement of C₄H₉N₃O₂ in biological fluids. This method involved precipitation of protein. Although several methods have been described since then, the original Jaffé technique is still the most widely used today. NS Biotec creatinine reagent is based on modified Jaffe reaction.

C₄H₉N₃O₂ in alkaline solution forms a yellow-red complex with alkaline picrate.