Intended Use
NSBioTec BioCelin reagent is intended for partial Thromboplastin (APTT) determination using ellagic acid , as an activator.
ASSAY PRINCIPLE
Cephaloplastin activates the coagulation factors of the intrinsic pathway of the coagulation mechanism in the presence of calcium ions. APTT is prolonged by deficiency of one or more of these clotting factors of the intrinsic pathway and in the presence of coagulation inhibitors like heparin .
REAGENT
BioCelin is a liquid ready to use activated cephaloplastin reagent for the determination of APTT. It is phospholipids preparation derived from rabbit brain with ellagic acid as an activator .
REAGENT STORAGE AND STABILITY
Store the reagent at 2 – 8 °C . Never freez the reagent . The reagent is stable up to the expiry date given on label when stored at 2 – 8 °C , 1 week at 18 – 25 °C , 2 days at 37 °C .
NOTE
1- Avoid exposure of the reagent to elevated temperature and contamination.
2- Immediately replace cap after use and store at recommended temperature.
3- Reagent contain 0.01 g/dl Thimerosal as a preservative .
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